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Genomics and Genetics Weekly

Susan Hasty, Publisher

Table of Contents . . . June 6th, 2003

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Genomics and Genetics Weekly | Other Publications

Cell Biology - Scientists find two forms of genetic material chromatin

SARS - Variant gives clues to origin of infection

Acute Lymphoblastic Leukemia - Gene dosage aids detection of 9p21 deletions in children

Gene Expression - Method achieves RNA interference in differentiated embryonic stem cells

Pharmacogenetics - Genomic structure, gene expression, promoter analysis of MRP7 characterized

Psoriasis - The S100A7 or psoriasin gene is duplicated 5 times in humans

Asthma - New gene discovery may lead to better classification

Autoimmune Disease Research - AIRE regulates negative selection of organ-specific T cells

Bioengineering - Controlled growth improves the yield of recombinant mouse endostatin from yeast

Breast Cancer - Molecular analysis of early lesions may be key to choosing best treatment

Crush Injury Syndrome - Genomics company works to treat injured in Turkey

DNA Repair - Defects in repair of DNA damage may impact neurodegeneration

DNA Sequencing - Method enables rapid determination of large cDNA's unknown 3' flanking sequence

Dendritic Cell Formation - Transcriptional factor Id2 functions to suppress B cell genes

Developmental Biology - Gene analysis finds "fingerprint" of defects in heart development

Diabetes Genomics and Genetics - High genetic liability for type 1 diabetes found among young Finnish twins

Diabetes Genomics and Genetics - NEUROD polymorphism Ala45Thr linked to type 1 diabetes in Czech children

Drug Side Effects - Scientists throw light on drug-induced weight gain

Endometrial Cancer - Gene mutation in some uterine tumors may signal that cancer runs in family

Finance - Grant awarded to develop gene expression analysis for cancer

Gene Regulation - Pattern recognition method zeroes in on cell's genetic machinery

Genetic Analysis - SSCP analysis via automated capillary array electrophoresis apparatus described

Genetic Testing - Public knows no more about genetics than in 1990

Geriatrics - Cell transplantation reveals clues about genes involved in aging

Helicobacter Pylori - The virulence gene cagA and MUC2 mucin are linked with cancer risk

Hepatitis D Virus - Cloned hepatitis delta virus genotype IIb thrives in cell cultures

Hereditary Periodic Fever - TNF-receptor associated periodic syndrome may be treatable with TNF receptors

Hutchinson-Gilford Progeria - Young "old" mice offer clue to premature aging

Imaging Technology - Atomic force microscopy and UV-laser ablation used for chromosomal dissection

Immunology - Kinetics, gene regulation in lymphocyte polarization to Th1 & Th2 cells studied

Immunology - Target and switch mechanism examined

Laboratory Techniques - Gene inactivation reversed in mice

Malaria Pathogenesis - Novel plasmodial gene family identified

Microarray Technology - SARS pathogen detection, resequencing array released

Neuroblastoma - Immune cells may help deliver cancer vaccines for children

Neurodegenerative Diseases - Nonepisodic autosomal dominant spinocerebellar ataxias have different mechanisms

Neuroscience - Dextromethorphan alters gene expression in certain areas of the brain

Obstetrics - Isolated fetal ascites must include consideration of Wolman disease

Ovarian Cancer - Tumor cell sensitivity - then resistance - to chemotherapy linked to gene

Pancreatic Cancer - Scientists uncover role of Fanconi anemia genes

SARS - Commercial lab test available

Spinal Cord Injury - Mice without Nogo exhibit axonal regeneration

Stem Cell Research - Alliance with NIA follows completion of analyses of precursor cells

Stem Cell Research - Genetically modified stem cells prevent juvenile diabetes in mice

Toxicology - Frequency of micronuclei changes based on tobacco use and genotoxic exposure

Tuberculosis - Gene that controls susceptibility discovered

Von Hippel-Lindau - Challenges in child rearing for families with hereditary disease

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