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Genomics and Genetics Weekly

Susan Hasty, Publisher

Table of Contents . . . April 2nd, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Genomics and Genetics Weekly | Other Publications

Cardiovascular Disease - GP Ialpha genotype affects CHD risk

Cancer Research - Movies of cells capture transmission of messages that control genes

Business & Finance - Genetic research planned at Cincinnati's new $115 million research facility

Breast Cancer - Estrogen interacts with estrogen receptor and SP proteins to control VEGF

Body Composition - A large-sample QTL study in mice examined body composition

Bacillus - Method to identify protease genes from B. thuringiensis developed

Atherosclerosis - Endothelial catalase overexpression attenuates oxidant-mediated injury

Alzheimer Disease - ACE gene polymorphism linked to damage in Alzheimer disease

Proteomics - Gene structure new member of Tieg family of proteins reported

Acute Coronary Syndrome - Analysis from TACTICS-TIMI 18 trial published

Oncogenes - Researchers find a protein that controls cell growth

Macular Degeneration - Search for eye disease genes narrows

Genomics & Genetics - Gene for vitamin K epoxide reductase identified

Developmental Biology - New method allows scientists to observe genes in action

Developmental Biology - Crucial brain development gene identified

Chronic Hepatitis B - Humanized anti-HBs Fab fragment may neutralize hepatitis B surface antigen

Collaborations - Aventis provided with early access to high-throughput GeneChip platform

DNA Vaccine - Altering conditions of DNA immunization allows control of immune response

Diagnostics - Generex developing kit for early detection of type 1 diabetes in young children

Diagnostics - Genomics company enters license agreement for nucleic acid arrays

Distribution Agreement - LSBC enters biomanufacturing and commercial distribution agreement

Epidemiology - Hepatitis C virus type 1 is the most prevalent genotype in central Italy

Evolution Research - Brains of chimps, humans closely related in gene expression

Evolutionary Biology - Yeast geneticists get a 2-for-1 deal

Eye Cancer - Rb protein's role in retina development is key to understanding retinoblastoma

Finance - Factive maker reports net losses for fourth quarter and fiscal year 2003

Finance - Molecular diagnostics company announces $34 million common stock sale

Friedreich Ataxia - Faulty DNA replication linked to neurological diseases

Gene Expression Analysis - RNAi, siRNA educational website launched

Gene Silencing - DNA-delivered RNAi products launched for research applications

Genomics - Molecular Staging provides whole genome amplification technology

Genomics & Genetics - Cardiac troponin I mutation linked to idiopathic dilated cardiomyopathy

Genomics & Genetics - X-linked gene elements leave women vulnerable to primary biliary cirrhosis

Genomics Toolkit - Collection of functional gene knockouts in a multicellular organism published

Genotyping - Diagnostics company launches high-speed genotyping service

HIV/AIDS - FDA authorizes a clinical study with Alferon LDO for HIV

HIV/AIDS Drug Resistance - Crystal structures of NNRT-resistant HIV RT characterized

HIV/AIDS Epidemiology - Ottawa HIV "superinfection" case did not carry superinfection

HIV/AIDS Proteomics - Assembly properties of HIV CA protein determined

HIV/AIDS RNA Research - Perinuclear HIV RNA release mediated by hRIP

HIV/AIDS RNA Studies - Antisense oligonucleotide scanning arrays reveal novel HIV leader RNA foldings

Hematology - Prostaglandin E1 enhances inhibition of platelet aggregation

Human Papillomavirus - Data demonstrate HPV testing catches more serious cervical disease

Hunter Syndrome - Patient enrollment completed in Hunter syndrome clinical trial

Huntington Disease - CRE-mediated transcription increased in Huntington disease

Infectious Disease - CIEF-WCID may enhance norovirus testing

Infectious Disease - Epidemiology of human M. bovis infection in U.K. characterized

Licensing Agreement - Endo enters agreement to codevelop new drugs for pain

Malaria Drug Resistance - Crt and Mdr1 orthologues not involved in P. chabaudi chloroquine resistance

Menopause - Ovarian failure changes reproductive mechanisms, not energy balance

Molecular Biology - Microchambers and interconnecting plumbing automate the gene isolation

Non-Small Cell Lung Cancer - p53 gene mutations are found in exhaled breath condensate of NSCLC patients

Oligodontia - Missense mutation in PAX9 causes non-syndromic oligodontia

Oncology - C-Myc inhibition shows the potential for treating liver cancer

Oncology - Signals for c-erbB-2 and VEGF combine to assess breast cancer prognosis

Osteoporosis - Estrogen receptor genotypes explain perimenopausal bone loss rates

Osteoporosis - MMP-9 gene changes associate with bone mineral density in men but not women

Osteoporosis - Premenopausal women show specific chromosomal links to bone mineral density

Personnel - Chief financial officer John McCarthy leaves genomics firm

Personnel - DNA-test provider appoints experts to its medical advisory board

Pharmaceutical & Drug Development - Microwave accelerated oligonucleotide labeling expands research possibilities

Protein Mapping - Protein-protein interaction map of virulence-related genes published

Regenerative Medicine - Interest in regenerative medicine heats up

Schizophrenia - Impaired AKT1-GSK3 beta signaling plays role in schizophrenia

Stem-Cell Research - New human embryonic cell lines to be made available to researchers

Stem-Cell Research - PU.1 supports proliferation of immature erythroid progenitors

Stem-Cell Research - U.S. lawmakers want to ease stem cell research restrictions

Thyroid Cancer - SAGE identifies genes that are differentially expressed in thyroid carcinoma

Virology - A new continuous nonradioactive assay monitors RNA polymerase activity

Virology - Key steps optimize the propagation of gene deleted Sendai virus vectors

Virology - Two-step purification confirms that RNA viruses replicate within RNP complexes

Women's Health - Genetics may play part in miscarriages

siRNA Targeting - siGENOME siRNA targets entire human genome

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