Cancer Therapy
Gene defect linked to premature aging
Published in Genomics and Genetics Weekly, May 21st, 2004
The findings, reported in the May 1, 2004, edition of Genes and Development, may provide a new target for therapies that force cancer cells to an early death.
The gene, called PASG (proliferation associated SNF2-like gene), normally works by decreasing the activity of other genes in two different ways: helping to add chemical groups to DNA, in a process known as methylation, or by modifying protein structures called histones that help wind DNA into compact coils.
"In order to grow and...
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