Published in Genomics and Genetics Weekly, May 21st, 2004
The findings, reported in the May 1, 2004, edition of Genes and Development, may provide a new target for therapies that force cancer cells to an early death.
The gene, called PASG (proliferation associated SNF2-like gene), normally works by decreasing the activity of other genes in two different ways: helping to add chemical groups to DNA, in a process known as methylation, or by modifying protein structures called histones that help wind DNA into compact coils.
"In order to grow and...
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