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Breast Cancer

Interleukin-12 intervenes in the growth of murine mammary tumors

According to a study from the United States, "interleukin-12 (IL-12) has potent antitumor activities via natural killer cells and cytotoxic T lymphocytes. However, the molecular mechanisms whereby IL-12 induces tumoricidal activities are poorly understood."

"Here, we report the genome-wide analysis of gene expression in a primary murine mammary carcinoma model that resembles human breast cancer, following the therapeutic application of recombinant IL-12, which restricted tumor growth and metastasis," said X.Y. Shi and colleagues, Cornell University, Weill Medical College.

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