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Genomics & Genetics Weekly

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Amyotrophic Lateral Sclerosis



Gene research shows Lou Gehrig disease may be treated or prevented



July 30th, 2004

Researchers at the University of Massachusetts Medical School (UMMS) and CytRx Corporation are investigating RNAi (RNA interference) gene silencing as a possible treatment or even cure for ALS.

RNA can be described as the on/off switch and RNAi may be seen as a way to turn off killer genes to stop physical degeneration.

"Tiny snippets of RNA with two strands, instead of the usual one strand, can be used to 'shut off' specific genes. We hope that in gene silencing CytRx can find treatments-and even cures-for such fatal diseases as ALS," says Dr. Jack Barber, scientific director of CytRx Corporation.

Sixty-three years after the...


Source: Genomics & Genetics Weekly (2004-07-30)

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