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Cancer Genomics and Genetics
Genes expressed in head and neck cancer identified
July 30th, 2004
A series of genes expressed in head and neck cancer have been identified through microarray analysis. In a recent study, scientists in the United States "applied a robust combinatorial (multi-test) approach to microarray data to identify genes consistently up- or downregulated in head and neck squamous cell carcinoma (HNSCC)." "RNA was extracted from 22 paired samples of HNSCC and normal tissue from the same donors and hybridized to the Affymetrix U95A chip," explained M.A. Kuriakose and coauthors at New York University. "Forty-two differentially expressed probe sets (representing 38 genes and one expressed sequence tag) satisfied all statistical...
Source: Genomics & Genetics Weekly (2004-07-30)
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