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Genomics & Genetics Weekly

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Cancer Therapy



Phase I trial of PXD101 begins in patients with hematologic cancer



July 30th, 2004

CuraGen Corp. (CRGN) and TopoTarget, A/S, announced the initiation of a phase I clinical trial to evaluate PXD101, a histone deacetylase (HDAC) inhibitor, in patients with hematologic cancer.

Given that PXD101 may play a role as a treatment for hematologic as well as solid cancers, this phase I trial complements the ongoing phase I study in cancer patients with solid tumors initiated in 2003.

"We are excited by the initiation of a second phase I for PXD101 as we look to explore the full potential of this promising cancer treatment," stated Timothy M. Shannon, MD, executive vice president of research and development and chief medical officer at...


Source: Genomics & Genetics Weekly (2004-07-30)

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