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Genomics & Genetics Weekly

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Cervical Cancer



P73 expression associated with cellular radiosensitivity after radiotherapy



July 30th, 2004

University of Hong Kong scientists suggest that expression of the p73 gene may be associated with cervical cancer cell radiosensitivity.

"By studying the gene expression profile with cDNA apoptotic array, the p73 gene was found overexpressed in radiosensitive cervical cancers when compared with radioresistant ones," said S.S. Liu and colleagues.

"To investigate the role of the p73 gene in relation to clinical assessment of radiosensitivity in cervical cancer based on the findings of residual tumor cells in cervical biopsies after completion of radiotherapy, we studied the protein expression of p73 in 59 cervical cancers after radiotherapy and 68...


Source: Genomics & Genetics Weekly (2004-07-30)

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