Genomics & Genetics Weekly
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DNA Synthesis
Pol X family members sponsor DNA repair and recombination
July 30th, 2004
Pol X family members sponsor DNA repair and recombination. According to published research from Switzerland, "DNA polymerases (pols) catalyze the synthesis of DNA. This reaction requires a primer-template DNA in order to grow from the 3'OH end of the primer along the template. On the other hand terminal deoxyribonucleotidyl transferase (TdT) catalyses the addition of nucleotides at the 3'OH end of a DNA strand, without the need of a template." "Pol lambda and pol mu are ubiquitous enzymes, possess both DNA polymerase and terminal deoxyribonucleotidyl transferase activities, and belong to the pol X family, together with pol beta and TdT. Here we show...
Source: Genomics & Genetics Weekly (2004-07-30)
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