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Genomics & Genetics Weekly

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Diabetic Neuropathy



Association of some polymorphic markers with diabetic polyneuropathy studied



July 30th, 2004

The association of polymorphic markers of the antioxidant enzyme genes with diabetic polyneuropathy has been examined.

Researchers from Russia compared "[t]he allele and genotype frequency distributions of polymorphic markers of genes coding for antioxidant enzymes ... for type 1 diabetes mellitus patients with or without diabetic polyneuropathy (DPN).

"The groups (total 180 patients) had nonoverlapping (polar) phenotypes. Group DPN+ included 86 patients with DPN and diabetic record no more than 5 years."

"Control group DPN-," E.V. Zotova and colleagues in Moscow explained, "included patients without DPN and diabetic record of at...


Source: Genomics & Genetics Weekly (2004-07-30)

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