Genomics & Genetics Weekly
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Diagnostics
New protein analysis helps scientists identify diseases in humans
July 30th, 2004
A new approach to protein analysis completed in the model organism yeast is helping scientists better identify diseases in humans. In the June 27 online issue of Nature Genetics, researchers at the Institute for Systems Biology (ISB) report that technology developed at the ISB and applied in a new way to yeast has led to an important new insight that could explain the molecular mechanism of Trichothiodystrophy, a rare human disease. The research, led by ISB scientist Dr. Jeff Ranish has used the Isotope Coded Affinity Tag (ICAT) method and quantitative mass spectrometry to find one or a few proteins that have specific properties in a complex...
Source: Genomics & Genetics Weekly (2004-07-30)
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