Genomics & Genetics Weekly
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Endocrinology
Molecular signals kindle the genetic forerunner of aldsterone synthase
July 30th, 2004
Molecular signals kindle the genetic forerunner of aldsterone synthase. "Aldosterone, the primary human mineralocorticoid, is a major regulator of intravascular volume and blood pressure. The capacity of the adrenal gland to produce aldosterone is controlled, in large part, by the regulated transcription of CYP11B2, the gene encoding aldosterone synthase," scientists writing in the journal Molecular and Cellular Endocrinology report. "Aldosterone synthase is responsible for the conversion of 11-deoxycorticosterone to aldosterone and is expressed only within the zona glomerulosa of the adrenal cortex," noted M.H. Bassett and colleagues,...
Source: Genomics & Genetics Weekly (2004-07-30)
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