Genomics & Genetics Weekly
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Allergy & Immunology
TNF-alpha and TGF-beta genotypes associated with allergic rhinitis and asthma
July 30th, 2004
TNF-alpha and TGF-beta genotypes are associated with allergic rhinitis and asthma. According to a study from the United States, "The development and expression of allergic rhinitis and asthma may be influenced by the elaboration of specific cytokines. Cytokine genotypes moderate illness severity in a variety of inflammatory disorders. "Cytokine genotyping was performed on 124 infants (85% white, 57% male) to determine whether specific cytokine genotypes are associated with a parental history of allergic rhinitis and/or asthma." "DNA was extracted from buccal brushings and assayed for tumor necrosis factor alpha (TNF-alpha),...
Source: Genomics & Genetics Weekly (2004-07-30)
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