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Anxiety Disorder
Serotonin transporter gene variation correlates with social phobia severity
August 6th, 2004
Serotonin transporter gene variation correlates with social phobia severity. "A functional polymorphism in the promoter region of the human serotonin transporter (5-HTT) gene has been related to negative affect and amygdala activity. We studied amygdala activation during social anxiety provocation in relation to affective ratings and 5-HTT genetic variation," researchers in Sweden report. "[H-2 O-15]positron emission tomography was used to estimate amygdala blood flow during private and public speaking (baseline and anxiety conditions) in 17 patients with social phobia," explained T. Furmark and colleagues, Uppsala University, Department of...
Source: Genomics & Genetics Weekly (2004-08-06)
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