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Breast Cancer
ER codon 594/HER2 codon 655 polymorphisms not associated with breast cancer risk
August 6th, 2004
ER codon 594 and HER2 codon 655 polymorphisms are not associated with an increased breast cancer risk. According to a study from Turkey, "The estrogen receptor (ER) and the human epithelial growth factor receptor 2 (HER2) genes have been implicated in the development and prognosis of breast cancer. "Several genetic polymorphic sites in these genes have been identified and associated with the risk of breast cancer. We have investigated the association between the estrogen receptor codon 594 (ACA to ACG) and HER2 codon 655 (ATC to GTC) polymorphisms and breast cancer risk." "Genomic DNA from breast cancer patients and control...
Source: Genomics & Genetics Weekly (2004-08-06)
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