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Genomics & Genetics Weekly

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DNA Research



Single-particle tracking suitable for DNA tether length studies



August 6th, 2004

A novel tracking method may improve measurements of DNA tether length.

Researchers in France devised "a simple single-particle tracking approach for monitoring the length of DNA molecules in tethered particle motion experiments."

"In this method, the trajectory of a submicroscopic bead tethered by a DNA molecule to a glass surface is determined by videomicroscopy coupled to image analysis," explained N. Pouget and coauthors at the National Center for Scientific Research (CNRS) in Toulouse. "The amplitude of motion of the bead is measured by the standard deviation of the distribution of successive positions of the bead in a given time...


Source: Genomics & Genetics Weekly (2004-08-06)

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