Genomics & Genetics Weekly
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Dermatology
Genetic studies of psoriasis susceptibility should focus on the PSORS1 locus
August 6th, 2004
Genetic studies of psoriasis susceptibility should focus on the PSORS1 locus. "Ten genome-wide scans have been conducted over the past few years in the search for psoriasis susceptibility genes, but only one potential susceptibility region has been consistently replicated. A meta-analysis using the genome-search meta-analysis method was undertaken combining the results of six of these psoriasis genome-wide studies. The results of this analysis revealed linkage to the major histocompatibility complex on chromosome 6p21 that includes the PSORS1 locus," scientists in England report. "In addition, linkage was also recorded to a region on chromosome...
Source: Genomics & Genetics Weekly (2004-08-06)
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