Genomics & Genetics Weekly
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Developmental Biology
Cell death protein has surprising role in cell migration
August 6th, 2004
By studying fruit fly ovaries, Johns Hopkins scientists have discovered that a protein known to block cell death also has the completely independent role of enabling normal cell movement. The discovery creates an unexpected new path to follow in the effort to understand the biochemical steps behind cells' movement, a critical aspect of embryonic development and the spread of cancer. The work was described in Cell. By studying fruit flies engineered to make extra use of random genes, the Hopkins team discovered that a protein called "inhibitor of apoptosis-1" (or IAP) can restore the tightly choreographed cellular movement that naturally occurs...
Source: Genomics & Genetics Weekly (2004-08-06)
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