Genomics & Genetics Weekly
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Diagnostics
Label-free gene sensors accelerate studies of nucleic acid binding events
August 6th, 2004
Label-free gene sensors accelerate studies of nucleic acid binding events. According to recent research from Germany, "the label-free detection of nucleic acid sequences is one of the modern attempts to develop quick, cheap and miniaturized hand-held devices for the future genetic testing in biotechnology and medical diagnostics. We present an approach to detect the hybridization of DNA sequences using electrolyte-oxide-semi conductor field-effect transistors (EOSFETs) with micrometer dimensions." "These semiconductor devices are sensitive to electrical charge variations that occur at the surface/electrolyte interface, i.e. upon hybridization of...
Source: Genomics & Genetics Weekly (2004-08-06)
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