Genomics & Genetics Weekly
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Diagnostics
Methylated DNA collected by tampons detects endometrial cancer
August 6th, 2004
Methylated DNA collected by tampons detects endometrial cancer. According to recent research published in the journal Cancer Epidemiology Biomarkers & Prevention, "This proof of principle study aimed to define a new and simple strategy for detection of endometrial cancer using epigenetic markers." "We investigated DNA isolated from vaginal secretion collected from tampon for aberrant methylation of five genes (CDH13, HSPA2, MLH1, RASSF1A and SOCS2) using MethyLight in 15 patients with endometrial cancer and 109 patients without endometrial cancer. "All endometrial cancer patients revealed three or more methylated genes," H....
Source: Genomics & Genetics Weekly (2004-08-06)
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