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Alcoholism
Microarray analysis identifies changes in liver gene expression
August 6th, 2004
Microarray analysis has been used to identify alcohol-induced changes in hepatic gene expression. "The mechanisms underlying alcoholic liver disease are not fully understood. It has been established that alcohol interferes with transcriptional and translational regulatory steps of cell function," scientists in Kentucky explained. "To understand such an effect, assessment of alcohol-induced changes in the simultaneous expression of a large number of genes may prove very useful." With this in mind, I.V. Deaciuc and colleagues at the University of Louisville conducted a study "to test a large number of genes (approximately 8,700) for possible changes in...
Source: Genomics & Genetics Weekly (2004-08-06)
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