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Alzheimer Disease
Effect of citalopram on lymphocyte gene expression characterized
August 6th, 2004
The effects of citalopram on lymphocyte gene expression have been characterized in cells from Alzheimer disease patients. "Antidepressants are widely used in the treatment of mood disorders associated with dementia," although "little information is available on their effect at the molecular level," neurologists in Hungary explained. "In certain neurodegenerative disorders, such as in Alzheimer disease, lymphocytes have been used to assess mirror changes that thought to occur in the brain," noted A. Palotas and colleagues at the University of Szeged. However, "[g]ene expression profiles of lymphocytes from Alzheimer patients have been shown to differ...
Source: Genomics & Genetics Weekly (2004-08-06)
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