Helicobacter Vaccine
Mechanisms of vaccine-induced protection against H. pylori reviewed
Published in Genomics and Genetics Weekly, December 10th, 2004
According to recent research from Germany, "Development of a vaccine against H. pylori is regarded as desirable alternative to the current antibiotic therapy regimens. Mice immunized with an attenuated recombinant Salmonella typhimurium expressing H. pylori urease subunits A and B have dramatically reduced bacterial loads after a single dose. The mechanisms of protection against this largely extra-cellular pathogen are not fully understood. The aim of this study was to identify genes that were regulated specifically...
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