Angiology
Genomic response to adrenoceptor activation determined in aortic smooth muscle
Published in Genomics and Genetics Weekly, December 10th, 2004
"Vascular adrenoceptors play an important role in vascular physiology and pathophysiology, such as hypertension, atherosclerosis and restenosis after angioplasty," scientists in China explained.
"To define the changes in the gene expression in vascular smooth muscle cells in response to the activation of alpha1 - or beta-adrenoceptors, a DNA microarray was used," in a study conducted by Y.Y. Wang and coauthors at Peking University. "First, the existence of alpha1 - and beta-adrenoceptors in A7r5 aortic smooth muscle cells was...
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