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Exercise Research

Daily running wheel activity in mice is affected by genetic background and sex

Published in Genomics and Genetics Weekly, March 4th, 2005

Researchers have investigated genetic influence on daily wheel-running activity level.

According to a study from the United States, "[Our] project was designed to determine the genetic (between-strain) and environmental (within-strain) variance in daily running wheel activity level in inbred mice."

J.T. Lightfoot and colleagues of the University of North Carolina in Charlotte described their study, "Five male and five female mice, 9.7 - 15.3 weeks old, from each of 13 strains (A/J, AKR/J, BALB/cJ, C3H/HeJ, C57Bl/6J, C57L/J, C3Heb/FeJ, CBA/J, DBA/2J, SWR/J, MRL/MpJ, SPRET/Ei, and CAST/Ei) as well as five female NZB/ BinJ mice were housed individually....

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