Matrix Metalloproteinases
Matrix metalloproteinase expression studied, role of oxidative stress revealed
Published in Genomics and Genetics Weekly, March 11th, 2005
"Matrix metalloproteinases are important biological effectors of tissue remodelling. Increased MMP expression occurs during injury, inflammation, cellular transformation, and oxidative stress. Oxidative stress in the lens, a causal factor in cataractogenesis, has been shown to induce MMP secretion," wrote M. John and colleagues, National Eye Institute.
"The objective of this study was to assess the expression of MMPs and their regulators in an oxidative stress model of cataract, where epithelial cell death and cortical...
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