Mitochondrial Disorder
Elucidating genetic bases of mitochondrial respiratory chain is essential
Published in Genomics and Genetics Weekly, March 11th, 2005
According to scientists writing in the journal Biochimica Et Biophysica Acta - Bioenergetics, "The mitochondrial respiratory chain (RC) results from the expression of both mitochondrial and nuclear genes. The number of disease-causing mutations in nuclear genes is steadily growing and mitochondrial DNA (mtDNA) deletions and mutations account for no more than 15-20% of pediatric patients. Unfortunately, the disease-causing mutations have been identified for only a small number of patients."
A. Rotig and colleagues of INSERM U393 in Paris continued, "Thus, elucidating...
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