Cardiac Development
Members of the T-box gene family are essential for normal heart development
Published in Genomics and Genetics Weekly, March 18th, 2005
According to the report from the United States, "Members of the T-box gene family (Tbx) are essential for normal heart development, and mutations in human TBX genes cause congenital cardiovascular malformations. T-box genes have been implicated in early cardiac lineage determination, chamber specification, valvuloseptal development, and diversification of the specialized conduction system in vertebrate embryos."
T.F. Plageman Jr. and K.E. Yutzey of Cincinnati Children's Hospital continued, "These genes include Tbx1, Tbx2, Tbx3, Tbx5, Tbx18, and...
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