Prostate Cancer

Age at diagnosis decreased over successive generations in PaC families

Published in Genomics and Genetics Weekly, July 29th, 2005

The age at prostate cancer (PaC) diagnosis has been seen to decrease over successive generations in PaC families.

"The decline in age at PaC diagnosis over the past decade is partially attributable to prostate specific antigen (PSA) screening. We examined age at diagnosis over successive generations within PaC families," researchers in the United States reported.

"Families with at least two affected men were selected from the University of Michigan Prostate Cancer Genetics Project. The 1,345 individuals from 489 families were grouped into three generations. Risk of PaC diagnosis at a given age was estimated to increase 1.31 (95% CI=1.13-1.51) times...

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Source: Genomics and Genetics Weekly (2005-07-29)

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