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Astrocytoma
Brain tumorigenesis linked to differential expression of HOX genes
July 14th, 2006
Brain tumorigenesis could be linked to the differential expression of HOX genes in normal and neoplastic astrocytes. According to recent research from the United States, "HOX genes are a large family of regulatory genes implicated in the control of developmental processes. HOX genes are involved in malignant transformation and progression of different types of tumour." "Despite intensive efforts to delineate the expression profiles of HOX genes in other cell types, nothing is known regarding the global expression profile of these genes in normal human astrocytes and astrocytomas," explained R. Abdelfattah and colleagues, University of Virginia. "The...
Source: Genomics & Genetics Weekly (2006-07-14)
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