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Genomics & Genetics Weekly

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Breast Cancer



Medullary breast cancer revealed in a subgroup of basal breast cancers



July 14th, 2006

A study from France has reported that gene expression profiling shows medullary breast cancer (MBC) is a subgroup of basal breast cancers.

"MBC is a rare but enigmatic pathologic type of breast cancer. Despite features of aggressiveness, MBC is associated with a favorable prognosis. Morphologic diagnosis remains difficult in many cases," wrote F. Bertucci and colleagues, Institut National de la Sante et de la Recherche Medicale.

"Very little is known about the molecular alterations involved in MBC. Notably, it is not clear whether MBC and ductal breast cancer (DBC) represent molecularly distinct entities and what genes/proteins might account for...


Source: Genomics & Genetics Weekly (2006-07-14)

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