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Genomics & Genetics Weekly

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Aging



Researchers find first proof that some molecular aspects of aging are out of our control



July 14th, 2006

A study led by Buck Institute faculty member Jan Vijg, PhD, provides the first direct evidence that the molecular machinery of our cells providing function to our tissues and organs spins irreversibly out of control as we age. The study appears in a recent edition of Nature.

The study identified and measured increases in random deviations in the activity of genes in aging mouse hearts. The work, done when Vijg was at the University of Texas Health Sciences Center in San Antonio, compared single cells from cardiac tissue in both young and old mice that were genetically identical, bred from the same genetic strain. Scientists focused on the activity of sets of...


Source: Genomics & Genetics Weekly (2006-07-14)

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