Apoptosis
Researchers from Germany, Japan and Australia report recent findings in apoptosis
Published in Genomics and Genetics Weekly, August 11th, 2006
Study 1: According to a study from Germany, loss of acinus inhibits oligonucleosomal DNA fragmentation but not chromatin condensation during apoptosis.
"Chromatin condensation and oligonucleosomal DNA fragmentation are the nuclear hallmarks of apoptosis. A proteolytic fragment of the apoptotic chromatin condensation inducer in the nucleus (Acinus), which is generated by caspase cleavage, has been implicated in mediating apoptotic chromatin condensation prior to DNA fragmentation.
"Acinus is also involved in mRNA splicing and a component of the...
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