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Dermatology

Researchers link a gene to aged skin problems and cancer

Published in Genomics and Genetics Weekly, October 6th, 2006

Oregon Health & Science University researchers have uncovered a pathway through which a gene's over-expression causes skin stem cells to switch from creating hair follicles to creating sebaceous glands.

The discovery by the laboratory of Xiao-Jing Wang, MD, PhD, professor of otolaryngology/head and neck surgery, OHSU School of Medicine, and member of the OHSU Cancer Institute, points to a new pathway that could some day be used as a therapeutic target for not only treating hair loss and oily skin, but prevent and treat cancer.

The study's results are published in a recent issue of the journal Developmental Cell.

Epidermal...

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