Thyroid Cancer
Papillary thyroid cancer with BRAF V600E mutation correlates with poorer outcomes
Published in Genomics and Genetics Weekly, November 10th, 2006
According to recent research from South Korea, "The BRAF mutation may influence the expression patterns of molecular markers that are related to the development and progression of thyroid cancer. The objective of the study was to investigate the effects of the BRAF V600E mutation on expression of galectin-3, cyclooxygenase-2, cyclin D1, p53, and vascular endothelial growth factor (VEGF) in PTC. One hundred sixty-three PTC and 28 nodular hyperplasia patients were selected retrospectively."
"The presence of the BRAF V600E mutation and the level of expression of the...
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