Melanoma
Recent findings in melanoma described by researchers from Norway, the United States and Japan
Published in Genomics and Genetics Weekly, November 10th, 2006
Study 1: Melanoma metastasis to the lungs may be prevented with anti-tissue factor gene therapy.
According to a study from Norway, "The coagulation trigger tissue factor has been implicated in tumor growth, angiogenesis, and metastasis. In this study, we explore the effects of ex vivo and in vivo delivery of short interfering RNA (siRNA) targeting tissue factor on B16 melanoma colonization of the lung in a murine model for metastasis."
"The purposes of this work are to establish a noncytotoxic in vivo model for investigation of tissue factor...
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