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Gene Therapy

Researchers from Yale University report details of new studies and findings in the area of gene therapy

Published in Genomics and Genetics Weekly, January 5th, 2007

A report, "Yeast recombination factor Rdh54 functionally interacts with the Rad51 recombinase and catalyzes Rad51 removal from DNA," is newly published data in Journal of Biological Chemistry. According to recent research published in the Journal of Biological Chemistry, "The Saccharomyces cerevisiae RDH54-encoded product, a member of the Swi2/Snf2 protein family, is needed for mitotic and meiotic interhomologue recombination and DNA repair. Previous biochemical studies employing Rdh54 purified from yeast cells have shown DNA-dependent ATP hydrolysis and DNA supercoiling by this protein, indicative of a DNA translocase function."

"Importantly, Rdh54...

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