Biological Chemistry
Recent findings from University of Vermont, Vermont Cancer Center highlight research in biological chemistry
Published in Genomics and Genetics Weekly, January 5th, 2007
Investigators publish new data in the report "Dynamics of bacteriophage T4 presynaptic filament assembly from extrinsic fluorescence measurements of Gp32-single-stranded DNA interactions. In the bacteriophage T4 homologous recombination system, presynaptic filament assembly on single-stranded (ssDNA) DNA requires UvsX recombinase, UvsY mediator, and Gp32 ssDNA-binding proteins. Gp32 exerts both positive and negative effects on filament assembly: positive by denaturing ssDNA secondary structure, and negative by competing with UvsX for ssDNA binding sites," scientists in the United States report.
"UvsY is believed to help UvsX displace Gp32 from the ssDNA. To test this...
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