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Osteoporosis Genetics

New osteoporosis genetics study findings recently were reported by researchers at University of Malta, Department of Pathology

Published in Genomics and Genetics Weekly, August 3rd, 2007

Investigators publish new data in the report "Linkage to chromosome 11p12 in two Maltese families with a highly penetrant form of osteoporosis." According to recent research from Malta, "Osteoporosis is a metabolic bone disease with a strong genetic component. Family-based linkage studies were performed by a number of investigators to try to identify loci that might contain genes responsible for an increased susceptibility to osteoporosis."

"A whole-genome linkage scan using 400 microsatellite markers was performed in 27 members from two Maltese families with a highly penetrant form of osteoporosis. The phenotype was defined by lumbar and femoral z-scores calculated...

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