Genomics & Genetics Weekly
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Colon Cancer
Research from F. Graziano and co-researchers provides new data on colon cancer
May 16th, 2008
According to recent research published in the Journal of Clinical Oncology, " Regulation of epidermal growth factor receptor (EGFR) signaling pathways may play a relevant role in determining the activity of cetuximab therapy in patients with metastatic colorectal cancer (MCRC). We investigated possible associations between genetic variants and clinical outcomes of MCRC patients treated with cetuximab-irinotecan salvage therapy." "Patients and Methods Patients who underwent cetuximab-irinotecan salvage therapy after disease progression during or after first-line bolus/infusional fluorouracil, leucovorin, and oxaliplatin chemotherapy and a second-line irinotecan-based...
Source: Genomics & Genetics Weekly (2008-05-16)
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