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Genomics & Genetics Weekly

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Alcoholism



Research results from Seoul National University, Medical Department update knowledge of alcoholism



July 4th, 2008

"Alcoholic chronic pancreatitis (ACP) develops in only a small number of alcoholics. Monocyte chemotactic protein-1 (MCP-1) and heat-shock protein 70-2 (HSP70-2) polymorphisms have been reported to be associated with the severity of acute pancreatitis," scientists in Seoul, South Korea report.

"However, their role in pathogenesis of ACP has not been investigated. A genetic association study for susceptibility and severity was performed on 79 male Korean ACP patients and 82 male controls. MCP-1 and HSP70-2 genotypes were determined using a fluorescence polarization detection method. The genotypes and G allele frequencies were no different in patients and controls....


Source: Genomics & Genetics Weekly (2008-07-04)

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