Genomics & Genetics Weekly
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Angiotensins
Research from Louisiana State University broadens understanding of angiotensins
July 4th, 2008
"We recently reported the presence of angiotensin-converting enzyme ( ACE) 2 in brain regions controlling cardiovascular function; however, the role of ACE2 in blood pressure regulation remains unclear because of the lack of specific tools to investigate its function. We hypothesized that ACE2 could play a pivotal role in the central regulation of cardiovascular function by regulating other renin - angiotensin system components," scientists in the United States report. "To test this hypothesis, we generated an adenovirus expressing the human ACE2 cDNA upstream of an enhanced green fluorescent protein (eGFP) reporter gene (Ad-hACE2-eGFP). In vitro characterization shows...
Source: Genomics & Genetics Weekly (2008-07-04)
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