Genomics & Genetics Weekly
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Celiac Disease
Research conducted at University of Bologna has updated our knowledge about celiac disease
July 4th, 2008
According to recent research from Bologna, Italy, "The prevalence of the recently described deamidated gliadin peptide antibodies was compared with that of the routinely used antigliadin, antiendomysial, and tissue transglutaminase antibodies in the sera of 128 untreated celiac patients and 134 controls. Sensitivity and specificity for celiac disease were 83.6 and 90.3% for IgA and 84.4 and 98.5% for IgG antibodies to deamidated gliadin peptides." "The new test displayed higher diagnostic accuracy than antigliadin antibodies and, although less sensitive than antiendomysial and tissue transglutaminase antibodies, showed significantly higher specificity than tissue...
Source: Genomics & Genetics Weekly (2008-07-04)
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