Genomics & Genetics Weekly
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DNA Research
Scientists at Kasetsart University publish research in DNA research
July 4th, 2008
"The development of novel DNA sensors is a crucial issue in the diagnosis of pathogenic and genetic diseases. We have used density functional theory (DFT) to investigate the performance of hybrid DNA sensors consisting of a gold atom (Au) deposited on two types of single-walled carbon nanotubes: armchair SWCNT(8,0)/Au and zigzag SWCNT(5,5)/Au and compared these with bare Au," scientists writing in the Journal of Molecular Graphics & Modelling report. "We also chose adenine:thymine (A:T) as a Watson-Crick base pair of the DNA double helix. In the recognition probe, SWCNT/Au/A, adenine is immobilized on the SWCNT/Au supporter via its active N7 anchor point. After...
Source: Genomics & Genetics Weekly (2008-07-04)
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