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Genomics & Genetics Weekly

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Drug Delivery



New findings from University of Paris describe advances in drug delivery



July 4th, 2008

According to a study from Chatenay-Malabry, France, "Proteocubosomic nanocarriers are three-dimensional (3D) self-assembly periodic nanofluidic structures that have a surface topology of open nanochannels, which is apparent also in natural and self-assembled viral capsids. Here, proteins are nanoconfined in a hydrated self-assembly mixture of amphiphilic monoolein (MO) and octylglucoside (OG) forming cubosomic nanostructures."

"The generated periodic 3D nanochannel network architectures are investigated by means of synchrotron X-ray diffraction. The structural behavior of the ternary MO/OG/transferrin and MO/OG immunoglobulin systems as well as the binary MO/OG mixture...


Source: Genomics & Genetics Weekly (2008-07-04)

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