Genomics & Genetics Weekly
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Genetics & Genomics
Studies from P. Liu et al in the area of genetics & genomics described
July 4th, 2008
According to recent research from Wuhan, People's Republic of China, "Ichthyosis vulgaris (IV) is one of the most commonly inherited disorders and has an estimated prevalence rate of 2.29% in China. To date, only one gene responsible for IV, the filaggrin gene (FLG), was identified, but genetic heterogeneity exists." "In this study, two Chinese families with autosomal-dominant IV were genetically characterized. The FLG gene was first excluded as the disease-causing gene in the two families. The larger family was then characterized by genome-wide linkage analysis to identify a new genetic locus for IV. Significant linkage was identified with markers on chromosome...
Source: Genomics & Genetics Weekly (2008-07-04)
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