Genomics & Genetics Weekly
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Prostatectomy
Research on prostatectomy detailed by B. Furusato and co-authors
July 4th, 2008
According to recent research from the United States, "Formalin-fixed paraffin-embedded (FFPE) prostate specimens are rich sources of molecular pathological information. However, FFPE-based microarray analysis of tissue samples may be hampered by the degradation and chemical alteration of RNA molecules due to the preservation procedure." "In this report, we employed a probe analyses of Affymetrix oligonucleotide arrays at individual probe level to compensate for the potential loss of gene identifications associated with compromised mRNA quality in FFPE preparations. Furthermore, to increase the sample quality, we utilized laser capture microdissection of prostate tumor...
Source: Genomics & Genetics Weekly (2008-07-04)
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