JAMA and Archives Journals

Statin does not appear helpful for children with learning disabilities caused by genetic disorder

Published in Genomics and Genetics Weekly, August 1st, 2008

Use of simvastatin by children with neurofibromatosis type 1 (NF1), a genetic disorder that can cause learning disabilities, did not result in improved cognitive function, according to a study in the July 16 issue of JAMA.

Characteristics of NF1 (incidence 1:3,000) include skin disorders, problems with small and large movement skills as well as the frequent occurrence of cognitive disabilities, such as visual-spatial skills, nonverbal long-term memory and attention span, according to background information in the article. Some NF1 studies involving mice suggested that use of a statin could improve cognitive deficits.

Lianne C. Krab, M.Sc., of Erasmus...

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Source: Genomics and Genetics Weekly (2008-08-01)

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