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University of Rochester Medical Center

Genes that control cell death fingered in age-related hearing loss

Published in Genomics and Genetics Weekly, November 7th, 2008

Several genes that play a role in how our body's cells normally auto-destruct may play a role in age-related hearing loss, according to research published online in the journal Apoptosis – a journal devoted to the topic of cell suicide, or programmed cell death.

Doctors know that genetics play some role in such hearing loss, which affects nearly everyone older than 60, as well as many people somewhat younger. But while more than 100 genes are known to play a role in congenital deafness, scientists have yet to pinpoint any gene in humans that plays a role in presbycusis, or age-related hearing loss.

The research in mice, done by using sophisticated...

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