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Genomics & Genetics Weekly

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Angiotensins



Reports summarize angiotensins study results from Medical University of Vienna



December 12th, 2008

According to recent research published in the European Journal of Clinical Investigation, " Angiotensin converting enzyme inhibitors (ACE-I) and angiotensin receptor blockers (ARB) exhibit beneficial antidiabetic effects in patients with type 2 diabetes independent of their blood pressure-lowering effects. Some antidiabetic properties of ARB and ACE-I might by exerted by activation of peroxisome proliferator-activated receptor gamma (PPAR gamma)."

"However, it is not clear whether this action is drug specific. Materials and methods The binding affinity of telmisartan, valsartan, lisinopril, rosiglitazone and angiotensin II to PPAR gamma was assessed in a...


Source: Genomics & Genetics Weekly (2008-12-12)

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